Sriram Vaidyanathan

Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification

Sriram Vaidyanathan, Krist Azizian, A.K.M. Ashiqul Haque et al. · Molecular Therapy — Nucleic Acids · 2018 · 264 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17

Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination

Renata M. Martin, Kazuya Ikeda, M. Kyle Cromer et al. · Cell stem cell · 2019 · 219 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Treatment of Chronic Rhinosinusitis With Nasal Polyposis With Oral Steroids Followed by Topical Steroids

Sriram Vaidyanathan, Martyn Barnes, Peter J. Williamson et al. · Annals of Internal Medicine · 2011 · 177 citations

Medicine, Otolaryngology, Pharmacotherapy +14

High-Efficiency, Selection-free Gene Repair in Airway Stem Cells from Cystic Fibrosis Patients Rescues CFTR Function in Differentiated Epithelia

Sriram Vaidyanathan, Ameen A. Salahudeen, Zachary M. Sellers et al. · Cell stem cell · 2019 · 132 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Global Transcriptional Response to CRISPR/Cas9-AAV6-Based Genome Editing in CD34+ Hematopoietic Stem and Progenitor Cells

M. Kyle Cromer, Sriram Vaidyanathan, Daniel E. Ryan et al. · Molecular Therapy · 2018 · 118 citations · Full text

Life Sciences, Genetics, Molecular Biology +14