Eli J. Fine

DNA targeting specificity of RNA-guided Cas9 nucleases

Patrick D. Hsu, David A. Scott, Joshua A. Weinstein et al. · Nature Biotechnology · 2013 · 4.9K citations · Full text

Life Sciences, Genetics, Molecular Biology +10

CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

Thomas J. Cradick, Eli J. Fine, Christopher J. Antico et al. · Nucleic Acids Research · 2013 · 604 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

Thomas J. Cradick, Peng Qiu, Ciaran M. Lee et al. · Molecular Therapy — Nucleic Acids · 2014 · 427 citations · Full text

Life Sciences, Bioinformatics, Genetics +13

TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity

Claudio Mussolino, Jamal Alzubi, Eli J. Fine et al. · Nucleic Acids Research · 2014 · 190 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Quantifying Genome-Editing Outcomes at Endogenous Loci with SMRT Sequencing

Ayal Hendel, Eric Kildebeck, Eli J. Fine et al. · Cell Reports · 2014 · 135 citations · Full text

Life Sciences, Genetics, Molecular Biology +14