Concepedia

Selecting Approaches for Hit Identification and Increasing Options by Building the Efficient Discovery of Actionable Chemical Matter from DNA-Encoded Libraries

Timothy L. Foley, Woodrow Burchett, Qiuxia Chen, Mark E. Flanagan, Brendon Kapinos, Xian-Yang Li, Justin I. Montgomery, Anokha S. Ratnayake, Hongyao Zhu, Marie‐Claire Peakman

SLAS DISCOVERY · 2021 · 50 citations · 51 references

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References

51

The Sequence of the Human Genome

J. Craig Venter, Mark D. Adams, Eugene W. Myers et al. · Science · 2001 · 13.7K citations

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Selective inhibition of BET bromodomains

P. Filippakopoulos, Jun Qi, S. Picaud et al. · Nature · 2010 · 4.3K citations · Full text

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Innovation in the pharmaceutical industry: New estimates of R&D costs

Joseph A. DiMasi, Henry G. Grabowski, Ronald W. Hansen · Journal of Health Economics · 2016 · 3.2K citations

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Maraviroc (UK-427,857), a Potent, Orally Bioavailable, and Selective Small-Molecule Inhibitor of Chemokine Receptor CCR5 with Broad-Spectrum Anti-Human Immunodeficiency Virus Type 1 Activity

Patrick Dorr, Mike Westby, Susan Dobbs et al. · Antimicrobial Agents and Chemotherapy · 2005 · 1.1K citations

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Moving beyond Rules: The Development of a Central Nervous System Multiparameter Optimization (CNS MPO) Approach To Enable Alignment of Druglike Properties

Travis T. Wager, Xinjun Hou, Patrick R. Verhoest et al. · ACS Chemical Neuroscience · 2010 · 1K citations

, , +17