Concepedia

Target Identification

Target Identification is a systematic process in drug discovery and chemical genomics whereby the specific molecular entity (typically a protein, nucleic acid, or pathway component) that mediates a relevant biological phenotype or disease and can be modulated by a chemical agent is determined and characterized as the primary target for therapeutic or mechanistic intervention.

491

Publications

35.2K

Citations

2.2K

Authors

789

Institutions

Publications per year

2017–2026

148

Parents

Children

Publications

491

Locating proteins in the cell using TargetP, SignalP and related tools

Olof Emanuelsson, Søren Brunak, Gunnar von Heijne et al. · Nature Protocols · 2007 · 3.2K citations

, , +11

Target identification using drug affinity responsive target stability (DARTS)

Brett Lomenick, Rui Hao, Nao Jonai et al. · Proceedings of the National Academy of Sciences · 2009 · 1.1K citations · Full text

, , +13

Therapeutic target database 2020: enriched resource for facilitating research and early development of targeted therapeutics

Yunxia Wang, Song Zhang, Fengcheng Li et al. · Nucleic Acids Research · 2019 · 830 citations · Full text

, , +17

Drug target validation and identification of secondary drug target effects using DNA microarrays

Matthew J. Marton, Joseph L. DeRisi, Holly A. Bennett et al. · Nature Medicine · 1998 · 647 citations

, , +14

TTD: <i>Therapeutic Target Database</i> describing target druggability information

Ying Zhou, Yintao Zhang, Donghai Zhao et al. · Nucleic Acids Research · 2023 · 585 citations · Full text

, , +11

1–5 of 491

Authors

2.2K

  1. HL
    Hongwei Liu

    Xidian University, China

    6 publications · 278 citations

    6

    h-index

  2. ID
    Ian Dunham

    Wellcome Sanger Institute, United Kingdom

    6 publications · 1.8K citations

    6

    h-index

  3. FZ
    Feng Zhu

    Zhejiang University, China

    5 publications · 1.9K citations

    5

    h-index

  4. LD
    Lan Du

    Xidian University, China

    5 publications · 101 citations

    5

    h-index

  5. DG
    David G. Hulcoop

    European Bioinformatics Institute, United Kingdom

    4 publications · 1.7K citations

    4

    h-index

1–5 of 2.2K

Institutions

789

  1. Harvard University

    Cambridge, United States

    11 h-index

    35 publications

    3.7K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    31 publications

    744 citations

  3. National University of Singapore

    Singapore, Singapore

    10 h-index

    43 publications

    7.8K citations

  4. Xidian University

    Xi'an, China

    9 h-index

    39 publications

    1.5K citations

  5. Chinese Academy of Sciences

    Beijing, China

    9 h-index

    27 publications

    1.1K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    18 publications

    3.7K citations

  7. European Bioinformatics Institute

    Cambridge, United Kingdom

    7 h-index

    89 publications

    33.7K citations

  8. The Ohio State University

    Columbus, United States

    7 h-index

    15 publications

    500 citations

1–8 of 789

Venues

  1. Nucleic Acids Research

    13 publications · 4.1K citations

    13

    h-index

  2. Drug Discovery Today

    11 publications · 462 citations

    11

    h-index

  3. PLoS ONE

    11 publications · 542 citations

    11

    h-index

  4. 11

    h-index

  5. Methods in molecular biology

    Book series · 10 publications · 520 citations

    10

    h-index

1–5