Concepedia

Structure-based Target Prediction

Structure-Based Target Prediction is a computational method in drug-target interaction mapping that leverages the three-dimensional structure of target proteins to infer potential binding partners, distinguishing itself from sequence- or ligand-based approaches by relying on structural complementarity and molecular docking principles.

116

Publications

9.9K

Citations

608

Authors

325

Institutions

Publications per year

2017–2026

53

Parents

Publications

116

Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods

Canrong Wu, Yang Liu, Yueying Yang et al. · Acta Pharmaceutica Sinica B · 2020 · 2.5K citations · Full text

, , +17

Predicting new molecular targets for known drugs

Michael J. Keiser, Vincent Setola, John J. Irwin et al. · Nature · 2009 · 1.7K citations

, , +12

DoGSiteScorer: a web server for automatic binding site prediction, analysis and druggability assessment

Andrea Volkamer, Daniel Kühn, Friedrich Rippmann et al. · Bioinformatics · 2012 · 604 citations · Full text

, , +17

Shaping the interaction landscape of bioactive molecules

David Gfeller, Olivier Michielin, Vincent Zoete · Bioinformatics · 2013 · 503 citations · Full text

, , +17

Potent effect of target structure on microRNA function

Dang Long, Rosalind Lee, Peter T. Williams et al. · Nature Structural & Molecular Biology · 2007 · 424 citations

, , +16

1–5 of 116

Authors

608

  1. MR
    Matthias Rarey

    Universität Hamburg, Germany

    3 publications · 693 citations

    3

    h-index

  2. GS
    Gisbert Schneider

    ETH Zurich, Switzerland

    3 publications · 104 citations

    3

    h-index

  3. AB
    Andreas Bender

    University of Cambridge, United Kingdom

    3 publications · 230 citations

    3

    h-index

  4. VN
    Vidya Niranjan

    Visvesvaraya Technological University, India

    2 publications · 66 citations

    2

    h-index

  5. TS
    Torsten Schwede

    University of Basel, Switzerland

    2 publications · 30 citations

    2

    h-index

1–5 of 608

Institutions

325

  1. Chinese Academy of Sciences

    Beijing, China

    7 h-index

    23 publications

    1.7K citations

  2. University of Chinese Academy of Sciences

    Beijing, China

    5 h-index

    20 publications

    1.8K citations

  3. Shanghai Institute of Materia Medica

    Pudong, China

    4 h-index

    31 publications

    2.5K citations

  4. Universität Hamburg

    Hamburg, Germany

    4 h-index

    13 publications

    2.9K citations

  5. Inserm

    Paris, France

    3 h-index

    8 publications

    161 citations

  6. Nankai University

    Tianjin, China

    3 h-index

    14 publications

    596 citations

  7. East China University of Science and Technology

    Shanghai, China

    3 h-index

    19 publications

    748 citations

  8. SIB Swiss Institute of Bioinformatics

    Lausanne, Switzerland

    3 h-index

    5 publications

    1.5K citations

1–8 of 325

Venues

  1. Journal of Chemical Information and Modeling

    JCIM · 10 publications · 518 citations

    10

    h-index

  2. Proteins Structure Function and Bioinformatics

    7 publications · 119 citations

    7

    h-index

  3. PLoS ONE

    5 publications · 103 citations

    5

    h-index

  4. Bioinformatics

    4 publications · 1.2K citations

    4

    h-index

  5. Journal of Molecular Graphics and Modelling

    4 publications · 214 citations

    4

    h-index

1–5