Concepedia

Resistance Mutation Mapping

Resistance Mutation Mapping is a methodological framework in virology and drug discovery that identifies and characterizes specific genetic alterations in viral genomes associated with reduced susceptibility to antiviral agents, thereby delineating the molecular determinants of resistance within target proteins.

100

Publications

7.7K

Citations

554

Authors

197

Institutions

Publications per year

2017–2026

12

Parents

Publications

100

Mutations in the P. falciparum Digestive Vacuole Transmembrane Protein PfCRT and Evidence for Their Role in Chloroquine Resistance

David A. Fidock, Takashi Nomura, Angela K. Talley et al. · Molecular Cell · 2000 · 1.5K citations · Full text

, , +12

Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine.

Paul Kellam, Charles A. Boucher, Brendan Larder · Proceedings of the National Academy of Sciences · 1992 · 420 citations

, , +17

RPS2, an Arabidopsis disease resistance locus specifying recognition of Pseudomonas syringae strains expressing the avirulence gene avrRpt2.

Barbara N. Kunkel, Andrew F. Bent, Douglas Dahlbeck et al. · The Plant Cell · 1993 · 313 citations · Full text

, , +17

Location of the major antigenic sites involved in rotavirus serotype-specific neutralization.

Mike Dyall‐Smith, I. Lazdins, Geoffrey W. Tregear et al. · Proceedings of the National Academy of Sciences · 1986 · 240 citations · Full text

, , +17

Development of Antiretroviral Drug Resistance

Mark A. Wainberg, Gerasimos J. Zaharatos, Bluma Brenner · New England Journal of Medicine · 2011 · 216 citations

, , +14

1–5 of 100

Authors

554

  1. DM
    Donald M. Coen

    Harvard University, United States

    4 publications · 422 citations

    4

    h-index

  2. JD
    Jesse D. Bloom

    Fred Hutch Cancer Center, United States

    3 publications · 281 citations

    3

    h-index

  3. KK
    Karen K. Biron

    Research Triangle Park Foundation, United States

    3 publications · 414 citations

    3

    h-index

  4. MT
    Mauro Tognon

    University of Ferrara, Italy

    2 publications · 24 citations

    2

    h-index

  5. JB
    Jolly Basak

    Visva-Bharati University, India

    2 publications · 130 citations

    2

    h-index

1–5 of 554

Institutions

197

  1. Fred Hutch Cancer Center

    Seattle, United States

    3 h-index

    9 publications

    783 citations

  2. Harvard University

    Cambridge, United States

    3 h-index

    17 publications

    1.6K citations

  3. University of Washington

    Seattle, United States

    3 h-index

    9 publications

    819 citations

  4. Monash University

    Melbourne, Australia

    3 h-index

    6 publications

    843 citations

  5. Assistance Publique – Hôpitaux de Paris

    Paris, France

    3 h-index

    10 publications

    233 citations

  6. University of Wisconsin–Madison

    Madison, United States

    3 h-index

    19 publications

    2.1K citations

  7. Université Paris Cité

    Paris, France

    2 h-index

    2 publications

    56 citations

  8. Délégation Paris 7

    Bagnolet, France

    2 h-index

    2 publications

    56 citations

1–8 of 197

Venues

  1. Journal of Virology

    JVI · 19 publications · 1.4K citations

    17

    h-index

  2. Virology

    7 publications · 428 citations

    7

    h-index

  3. Antimicrobial Agents and Chemotherapy

    AAC · 6 publications · 363 citations

    6

    h-index

  4. Archives of Virology

    4 publications · 59 citations

    4

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 695 citations

    3

    h-index

1–5