Jesse D. Bloom

Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding

Tyler N. Starr, Allison J. Greaney, Sarah K. Hilton et al. · Cell · 2020 · 2.2K citations · Full text

Viral Diagnostics, Viral Pathogenesis, Immunology +19

Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies

Allison J. Greaney, Andrea N. Loes, Katharine H. D. Crawford et al. · Cell Host & Microbe · 2021 · 1.3K citations · Full text

Viral Evolution, Viral Diagnostics, Medicine +9

Protein stability promotes evolvability

Jesse D. Bloom, Sy T. Labthavikul, Christopher R. Otey et al. · Proceedings of the National Academy of Sciences · 2006 · 1.2K citations · Full text

Protein Assembly, Molecular Biology, Mutational Robustness +17

Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition

Allison J. Greaney, Tyler N. Starr, Pavlo Gilchuk et al. · Cell Host & Microbe · 2020 · 1.1K citations · Full text

Protocol and Reagents for Pseudotyping Lentiviral Particles with SARS-CoV-2 Spike Protein for Neutralization Assays

Katharine H. D. Crawford, Rachel Eguia, Adam S. Dingens et al. · Viruses · 2020 · 866 citations · Full text

Spike Protein, Sars-cov-2 Spike, Synthetic Virology +14