Assay Guidance Manual [Internet]

Sarine Markossian, A Grossman, Kyle R. Brimacombe, +31

Pharmaceutical ResearchDrug TargetBiochemistryHigh Throughput ScreeningMedicine +13

Manipulation of Carrier Proteins in Antibiotic Biosynthesis

James J. La Clair, Timothy L. Foley, Tracy R Schegg, +2

Chemistry & Biology

BiosynthesisEngineeringBiochemistryNatural SciencesProtein Biosynthesis +4

Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation

Laura A. McAllister, Christopher R. Butler, Scot Mente, +20

Journal of Medicinal Chemistry

Chemical BiologyMedicinal ChemistryPharmaceutical ScienceCompound 15Biochemistry +12

Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase

Christopher R. Butler, Elizabeth Beck, Anthony R. Harris, +19

Journal of Medicinal Chemistry

Covalent InhibitorsBioorganic ChemistrySelective Magl InhibitorPharmacotherapyPiperidine Carbamates +15

4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-<i>N</i>-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide (ML267), a Potent Inhibitor of Bacterial Phosphopantetheinyl Transferase That Attenuates Secondary Metabolism and Thwarts Bacterial Growth

Timothy L. Foley, Ganesha Rai, Adam Yasgar, +9

Journal of Medicinal Chemistry

An Orthogonal Active Site Identification System (OASIS) for Proteomic Profiling of Natural Product Biosynthesis

Jordan L. Meier, Sherry Niessen, Heather Hoover, +3

ACS Chemical Biology

EngineeringGene RecognitionProteomic TechnologyBiosynthesisNatural Product Biosynthesis +14

Interlaboratory testing of the transferability of a candidate reference method for total cholesterol in serum.

G R Cooper, S J Smith, Irma W. Duncan, +7

Clinical Chemistry

Lipid AnalysisEngineeringReference MethodHyperlipidemiaVerification And Validation +15

delta-Aminolevulinic acid synthase from Euglena gracilis.

S I Beale, Timothy L. Foley, Valdis A. Dzelzkalns

Proceedings of the National Academy of Sciences

Ala Synthase ActivityAla SynthaseBiosynthesisBioorganic ChemistryEngineering +11

Selecting Approaches for Hit Identification and Increasing Options by Building the Efficient Discovery of Actionable Chemical Matter from DNA-Encoded Libraries

Timothy L. Foley, Woodrow Burchett, Qiuxia Chen, +7

SLAS DISCOVERY

A Solution Phase Platform to Characterize Chemical Reaction Compatibility with DNA-Encoded Chemical Library Synthesis

Anokha S. Ratnayake, Mark E. Flanagan, Timothy L. Foley, +5

ACS Combinatorial Science

Combinatorial ChemistryBioorganic ChemistryEngineeringChemical TransformationDna Analysis +17