Christopher R. Butler

Molecular Transformer unifies reaction prediction and retrosynthesis across pharma chemical space

Alpha A. Lee, Qingyi Yang, Vishnu Sresht et al. · Chemical Communications · 2019 · 140 citations

Vinylation of Aromatic Halides Using Inexpensive Organosilicon Reagents. Illustration of Design of Experiment Protocols

Scott E. Denmark, Christopher R. Butler · Journal of the American Chemical Society · 2008 · 106 citations · Full text

Room Temperature, Chemical Engineering, Cross-coupling Reaction +13

Palladium- (and nickel-) catalyzed vinylation of aryl halides

Scott E. Denmark, Christopher R. Butler · Chemical Communications · 2008 · 89 citations · Full text

Aryl Halides, Chemical Engineering, Engineering +12

Vinylation of Aryl Bromides Using an Inexpensive Vinylpolysiloxane

Scott E. Denmark, Christopher R. Butler · Organic Letters · 2005 · 82 citations

Substituted Styrenes, Engineering, Organic Chemistry +16

Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug–Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors

Michael A. Brodney, Elizabeth M. Beck, Christopher R. Butler et al. · Journal of Medicinal Chemistry · 2015 · 78 citations · Full text

Reduce Risk, Drug Target, Peptide Science +21