Concepedia

Inhibition of cellular communication network factor 1 (CCN1)-driven senescence slows down cartilage inflammaging and osteoarthritis

Meng Feng, Peng Hang, Ricky Yao, Zhifeng Zhang, Genwen Mao, Haiquan Yu, Yusheng Qiu

Bone · 2020 · 38 citations · 26 references

DOI

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References

26

Senolytics improve physical function and increase lifespan in old age

Ming Xu, Tamar Pirtskhalava, Joshua N. Farr et al. · Nature Medicine · 2018 · 2.2K citations

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A complex secretory program orchestrated by the inflammasome controls paracrine senescence

Juan Carlos Acosta, Ana Banito, Torsten Wüestefeld et al. · Nature Cell Biology · 2013 · 2.2K citations · Full text

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Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment

Ok Hee Jeon, Chaekyu Kim, Remi-Martin Laberge et al. · Nature Medicine · 2017 · 1.5K citations · Full text

, , +17

The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

Joon-Il Jun, Lester F. Lau · Nature Cell Biology · 2010 · 960 citations · Full text

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The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the rabbit

Sheila Laverty, Christiane Girard, James M. Williams et al. · Osteoarthritis and Cartilage · 2010 · 293 citations · Full text

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