Concepedia

Cartilage Destruction

Cartilage Destruction is a pathophysiological process characterized by the progressive degradation of articular cartilage matrix components, primarily mediated by inflammatory and enzymatic mechanisms in the context of autoimmune rheumatic diseases.

3.8K

Publications

215.8K

Citations

16.4K

Authors

2.7K

Institutions

Publications per year

2017–2026

1.4K

Parents

Publications

3.8K

Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

S.S. Glasson, Roger Askew, Barbara Sheppard et al. · Nature · 2005 · 1.3K citations

, , +14

The role of cytokines in osteoarthritis pathophysiology

Julio Fernandes, Johanne Martel‐Pelletier, Jean‐Pierre Pelletier · Biorheology · 2002 · 1K citations

, , +17

The Effect of Glucocorticoids on Joint Destruction in Rheumatoid Arthritis

John Kirwan · New England Journal of Medicine · 1995 · 807 citations · Full text

, , +13

Treatment with a neutralizing anti‐murine interleukin‐17 antibody after the onset of collagen‐induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion

Erik Lubberts, Marije I. Koenders, Birgitte Oppers‐Walgreen et al. · Arthritis & Rheumatism · 2004 · 703 citations

, , +17

MicroRNA-140 plays dual roles in both cartilage development and homeostasis

Shigeru Miyaki, Tempei Sato, Atsushi Inoue et al. · Genes & Development · 2010 · 671 citations · Full text

, , +16

1–5 of 3.8K

Authors

16.4K

  1. WB
    Wim B. van den Berg

    Radboud University Nijmegen, Netherlands

    82 publications · 9.5K citations

    49

    h-index

  2. LA
    Leo A. B. Joosten

    Radboud University Nijmegen, Netherlands

    34 publications · 6.4K citations

    30

    h-index

  3. ML
    Martin Lotz

    Scripps Research Institute, United States

    29 publications · 4.7K citations

    28

    h-index

  4. SG
    Steffen Gay

    University Hospital of Zurich, Switzerland

    24 publications · 2K citations

    24

    h-index

  5. FA
    Fons A. J. van de Loo

    Radboud University Nijmegen, Netherlands

    23 publications · 3.9K citations

    22

    h-index

1–5 of 16.4K

Institutions

2.7K

  1. Radboud University Nijmegen

    Nijmegen, The Netherlands

    61 h-index

    489 publications

    55.8K citations

  2. Rush University Medical Center

    Chicago, United States

    42 h-index

    194 publications

    14.6K citations

  3. Radboud University Medical Center

    Nijmegen, The Netherlands

    41 h-index

    295 publications

    31.9K citations

  4. Lund University

    Lund, Sweden

    31 h-index

    134 publications

    9.2K citations

  5. McGill University

    Montreal, Canada

    30 h-index

    91 publications

    12.9K citations

  6. Wenzhou Medical University

    Wenzhou, China

    30 h-index

    347 publications

    13.8K citations

  7. Southern Medical University

    Guangzhou, China

    30 h-index

    204 publications

    11.8K citations

  8. Harvard University

    Cambridge, United States

    29 h-index

    96 publications

    6.1K citations

1–8 of 2.7K

Venues

  1. Arthritis & Rheumatism

    311 publications · 32.9K citations

    105

    h-index

  2. Osteoarthritis and Cartilage

    170 publications · 11.3K citations

    65

    h-index

  3. Annals of the Rheumatic Diseases

    ARD · 134 publications · 11.5K citations

    62

    h-index

  4. Arthritis Research & Therapy

    128 publications · 9.8K citations

    61

    h-index

  5. PubMed

    Repository · 332 publications · 14.1K citations

    60

    h-index

1–5