Concepedia

Cellular Senescence

Cellular Senescence is a permanent state of cell cycle arrest in individual cells, typically triggered by various forms of cellular stress or damage, that serves as a key mechanism in aging and age-related diseases by preventing the proliferation of dysfunctional cells.

11.6K

Publications

983.6K

Citations

55.1K

Authors

6.2K

Institutions

Publications per year

2017–2026

4.3K

Parents

Children

Publications

11.6K

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

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Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

Nam W. Kim, Mieczyslaw A. Piatyszek, Karen R. Prowse et al. · Science · 1994 · 7.1K citations

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Telomeres shorten during ageing of human fibroblasts

Calvin B. Harley, A. B. Futcher, Carol W. Greider · Nature · 1990 · 5.7K citations

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Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell · 1997 · 5.1K citations · Full text

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Extension of Life-Span by Introduction of Telomerase into Normal Human Cells

Andrea Bodnár, Michel Ouellette, Maria Frolkis et al. · Science · 1998 · 5K citations

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1–5 of 11.6K

Authors

55.1K

  1. JC
    Judith Campisi

    Buck Institute for Research on Aging, United States

    103 publications · 34.5K citations

    77

    h-index

  2. JL
    James L. Kirkland

    Mayo Clinic in Florida, United States

    83 publications · 23.8K citations

    52

    h-index

  3. TT
    Tamar Tchkonia

    Mayo Clinic in Florida, United States

    75 publications · 22.7K citations

    49

    h-index

  4. JF
    João F. Passos

    Newcastle University, United Kingdom

    52 publications · 15.9K citations

    40

    h-index

  5. MS
    Manuel Serrano

    Spanish National Cancer Research Centre, Spain

    43 publications · 14.7K citations

    37

    h-index

1–5 of 55.1K

Institutions

6.2K

  1. Harvard University

    Cambridge, United States

    95 h-index

    814 publications

    162.4K citations

  2. Lawrence Berkeley National Laboratory

    Berkeley, United States

    79 h-index

    283 publications

    178K citations

  3. Inserm

    Paris, France

    77 h-index

    1.5K publications

    121K citations

  4. Buck Institute for Research on Aging

    Novato, United States

    75 h-index

    474 publications

    156.1K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    72 h-index

    1K publications

    79.4K citations

  6. National Institutes of Health

    Bethesda, United States

    71 h-index

    735 publications

    118.2K citations

  7. Mayo Clinic

    Rochester, United States

    63 h-index

    639 publications

    196.3K citations

  8. Mayo Clinic in Florida

    Jacksonville, United States

    62 h-index

    612 publications

    150.7K citations

1–8 of 6.2K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 189 publications · 48.2K citations

    108

    h-index

  2. Aging Cell

    340 publications · 34.2K citations

    100

    h-index

  3. Nature

    103 publications · 68.5K citations

    83

    h-index

  4. Aging

    314 publications · 19.8K citations

    76

    h-index

  5. PubMed

    Repository · 352 publications · 21.3K citations

    74

    h-index

1–5