João F. Passos

Cellular senescence mediates fibrotic pulmonary disease

Marissa J. Schafer, Thomas A. White, Koji Iijima et al. · Nature Communications · 2017 · 1.5K citations · Full text

Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease

LaTonya J. Hickson, Larissa Prata, Shane A. Bobart et al. · EBioMedicine · 2019 · 1.2K citations · Full text

Cellular senescence drives age-dependent hepatic steatosis

Mikołaj Ogrodnik, Satomi Miwa, Tamar Tchkonia et al. · Nature Communications · 2017 · 987 citations · Full text

Feedback between p21 and reactive oxygen production is necessary for cell senescence

João F. Passos, Glyn Nelson, Chunfang Wang et al. · Molecular Systems Biology · 2010 · 971 citations · Full text

Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence

Graeme Hewitt, Diana Jurk, Francisco Madeira Marques et al. · Nature Communications · 2012 · 883 citations · Full text

Dna Damage, Aging, Genetics +16