Mikołaj Ogrodnik

Senolytics improve physical function and increase lifespan in old age

Ming Xu, Tamar Pirtskhalava, Joshua N. Farr et al. · Nature Medicine · 2018 · 2.2K citations

Education, Geriatric Medicine, Physiology +14

Targeting cellular senescence prevents age-related bone loss in mice

Joshua N. Farr, Ming Xu, Megan Weivoda et al. · Nature Medicine · 2017 · 1.1K citations · Full text

Medicine, Geriatric Medicine, Aging +9

Cellular senescence drives age-dependent hepatic steatosis

Mikołaj Ogrodnik, Satomi Miwa, Tamar Tchkonia et al. · Nature Communications · 2017 · 1K citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age

Ming Xu, Tamar Tchkonia, Husheng Ding et al. · Proceedings of the National Academy of Sciences · 2015 · 892 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice

Carolyn M Roos, Bin Zhang, Allyson K. Palmer et al. · Aging Cell · 2016 · 723 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17