Concepedia

Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer

Xiaoguang Liu, Kellen Olszewski, Yilei Zhang, Esther W. Lim, Jiejun Shi, Xiaoshan Zhang, Jie Zhang, Hyemin Lee, Pranavi Koppula, Guang Lei,

Nature Cell Biology · 2020 · 595 citations · 41 references

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41

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al. · Cell · 2012 · 18.1K citations · Full text

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Glucose feeds the TCA cycle via circulating lactate

Sheng Hui, Jonathan M. Ghergurovich, Raphael J. Morscher et al. · Nature · 2017 · 1.7K citations

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Lactate Metabolism in Human Lung Tumors

Brandon Faubert, Kevin Y. Li, Ling Cai et al. · Cell · 2017 · 1.3K citations · Full text

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AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress

Sang‐Min Jeon, Navdeep S. Chandel, Nissim Hay · Nature · 2012 · 1.1K citations

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Quantitative flux analysis reveals folate-dependent NADPH production

Jing Fan, Jiangbin Ye, Jurre J. Kamphorst et al. · Nature · 2014 · 1.1K citations · Full text

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