Nissim Hay

AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress

Sang‐Min Jeon, Navdeep S. Chandel, Nissim Hay · Nature · 2012 · 1.1K citations

Life Sciences, Cancer Biology, Oncology +16

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

Scott Kennedy, Andrew J. Wagner, Suzanne D. Conzen et al. · Genes & Development · 1997 · 1.1K citations · Full text

Life Sciences, Cell Biology, Apoptosis +16

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

Kathrin Gottlob, Nathan Majewski, Scott Kennedy et al. · Genes & Development · 2001 · 948 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Growth retardation and increased apoptosis in mice with homozygous disruption of the <i>akt1</i> gene

William S. Chen, Pei-Zhang Xu, Kathrin Gottlob et al. · Genes & Development · 2001 · 922 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

Anne‐Claude Gingras, Scott Kennedy, Maura O'Leary et al. · Genes & Development · 1998 · 885 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13