Esther W. Lim

Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer

Xiaoguang Liu, Kellen Olszewski, Yilei Zhang et al. · Nature Cell Biology · 2020 · 595 citations · Full text

Life Sciences, Biochemistry, Cancer Biology +17

Serine restriction alters sphingolipid diversity to constrain tumour growth

Thangaselvam Muthusamy, Thekla Cordes, Michal K. Handzlik et al. · Nature · 2020 · 314 citations · Full text

Medicine, Cancer Biology, Oncology +14

γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A

Xue Gao, Liang Zhao, Shuangping Liu et al. · Molecular Cell · 2019 · 83 citations · Full text

Life Sciences, Biochemistry, Cell Biology +9

Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy

Isaac Perea‐Gil, Timon Seeger, Arne A.N. Bruyneel et al. · European Heart Journal · 2022 · 71 citations · Full text

Medicine, Cardiology, Molecular Medicine +13

Extracellular serine and glycine are required for mouse and human skeletal muscle stem and progenitor cell function

Brandon Gheller, Jamie Blum, Esther W. Lim et al. · Molecular Metabolism · 2020 · 70 citations · Full text

Life Sciences, Biochemistry, Physiology +17