BAP1 links metabolic regulation of ferroptosis to tumour suppression

Yilei Zhang, Jiejun Shi, Xiaoguang Liu, +15

Nature Cell Biology

BiochemistryMetabolic RegulationTumor SuppressorMedicineCell Biology +3

Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer

Xiaoguang Liu, Kellen Olszewski, Yilei Zhang, +14

Nature Cell Biology

Disulfide StressTargetable Metabolic VulnerabilityCystine Transporter RegulationBiochemistryMedicine +10

A targetable CoQ-FSP1 axis drives ferroptosis- and radiation-resistance in KEAP1 inactive lung cancers

Pranavi Koppula, Guang Lei, Yilei Zhang, +11

Nature Communications

The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate

Pranavi Koppula, Yilei Zhang, Jiejun Shi, +2

Journal of Biological Chemistry

Defining the Independence of the Liver Circadian Clock

Kevin B. Koronowski, Kenichiro Kinouchi, Patrick-Simon Welz, +11

Cell

SleepAlertnessHepatologyHealth SciencesMedicine +9

Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation

Leah Gates, Jiejun Shi, Aarti D. Rohira, +11

Journal of Biological Chemistry

Histone ModificationsChromatinTranscriptional RegulationHistone H3Developmental Biology +13

Integration of feeding behavior by the liver circadian clock reveals network dependency of metabolic rhythms

Carolina M. Greco, Kevin B. Koronowski, Jacob G. Smith, +26

Science Advances

NutritionMetabolic RhythmsHomeostatic MechanismFood IntakeObesity +21

Recognition of histone acetylation by the GAS41 YEATS domain promotes H2A.Z deposition in non-small cell lung cancer

Chih-Chao Hsu, Jiejun Shi, Chao Yuan, +8

Genes & Development

Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer

Ze‐Yi Zheng, Meenakshi Anurag, Jonathan T. Lei, +28

Cancer Cell

The concurrence of DNA methylation and demethylation is associated with transcription regulation

Jiejun Shi, Jianfeng Xu, Yiling Elaine Chen, +5

Nature Communications