FGFR3 deficiency enhances CXCL12-dependent chemotaxis of macrophages via upregulating CXCR7 and aggravates joint destruction in mice

Synovial macrophage M1 polarisation exacerbates experimental osteoarthritis partially through R-spondin-2

Haiyan Zhang, C. X. Lin, Chun Zeng et al. · Annals of the Rheumatic Diseases · 2018 · 507 citations

Medicine, Cell Biology, Immunology +17

NF-κB activation provides the potential link between inflammation and hyperplasia in the arthritic joint

Alexei Miagkov, Chadwick E. Brown, John Didsbury et al. · Proceedings of the National Academy of Sciences · 1998 · 465 citations · Full text

Life Sciences, Immunology, Pathobiology +15

Stromal Cell-Derived Factor-1-CXC Chemokine Receptor 4 Interactions Play a Central Role in CD4+ T Cell Accumulation in Rheumatoid Arthritis Synovium

Toshihiro Nanki, Kenji Hayashida, Hani El‐Gabalawy et al. · The Journal of Immunology · 2000 · 457 citations · Full text

Life Sciences, Cell Biology, Immunology +17

CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis

Harini Raghu, Christin M. Lepus, Qian Wang et al. · Annals of the Rheumatic Diseases · 2016 · 445 citations

Life Sciences, Immunology, Orthopaedic Surgery +17

Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis

Arjen B. Blom, Peter L. E. M. van Lent, A. E. M. Holthuysen et al. · Osteoarthritis and Cartilage · 2004 · 373 citations · Full text

Medicine, Cell Biology, Immunology +11