Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations

Jeremy Sokolove, Christin M. Lepus

Therapeutic Advances in Musculoskeletal Disease

ImmunologyOa JointMusculoskeletal ResearchOrthopaedic SurgeryAxial Spondyloarthritis +14

Identification of a central role for complement in osteoarthritis

Qian Wang, Andrew Rozelle, Christin M. Lepus, +22

Nature Medicine

InflammationRheumatologyComplement SystemCentral RoleRheumatoid Disorder +6

CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis

Harini Raghu, Christin M. Lepus, Qian Wang, +9

Annals of the Rheumatic Diseases

Diacylglycerol Enrichment of Endoplasmic Reticulum or Lipid Droplets Recruits Perilipin 3/TIP47 during Lipid Storage and Mobilization

James R. Skinner, Trevor M. Shew, Danielle M. Schwartz, +4

Journal of Biological Chemistry

Brief Report: Citrullination Within the Atherosclerotic Plaque: A Potential Target for the Anti–Citrullinated Protein Antibody Response in Rheumatoid Arthritis

Jeremy Sokolove, Matthew Brennan, Orr Sharpe, +7

Arthritis & Rheumatism

IgE-mediated mast cell activation promotes inflammation and cartilage destruction in osteoarthritis

Qian Wang, Christin M. Lepus, Harini Raghu, +18

eLife

Comparison of human fetal liver, umbilical cord blood, and adult blood hematopoietic stem cell engraftment in NOD-scid/γc−/−, Balb/c-Rag1−/−γc−/−, and C.B-17-scid/bg immunodeficient mice

Christin M. Lepus, Thomas F. Gibson, Scott A. Gerber, +10

Human Immunology

Human Fetal LiverCell TherapyDevelopmental BiologyMedicineUmbilical Cord Blood +12

Multilayer nanofilms as substrates for hepatocellular applications

Corinne R. Wittmer, Jennifer A. Phelps, Christin M. Lepus, +3

Biomaterials

EngineeringNanomaterialsNanobiotechnologyNanotechnologyHepatocellular Applications +1

Dysregulated integrin αVβ3 and CD47 signaling promotes joint inflammation, cartilage breakdown, and progression of osteoarthritis

Qian Wang, Kazuhiro Onuma, Changhao Liu, +21

JCI Insight

Cartilage BreakdownJoint FailureImmunologyImmune RegulationIntegrin Function +18

Brief Report: Carboxypeptidase B Serves as a Protective Mediator in Osteoarthritis

Christin M. Lepus, Jason Jungsik Song, Qian Wang, +6

Arthritis & Rheumatology