Concepedia

Joint Destruction

Joint destruction is a pathological process characterized by the irreversible structural degradation of articular cartilage and subchondral bone within a synovial joint, typically resulting from unchecked inflammatory or infectious mechanisms such as those seen in septic arthritis.

1.5K

Publications

88.6K

Citations

7.2K

Authors

1.8K

Institutions

Publications per year

2017–2026

300

Parents

Publications

1.5K

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

Young‐Yun Kong, Ulrich Feige, Iidiko Sarosi et al. · Nature · 1999 · 1.9K citations

, , +17

Benefit of very early referral and very early therapy with disease-modifying anti-rheumatic drugs in patients with early rheumatoid arthritis

Valerie Nell · British journal of rheumatology · 2004 · 816 citations · Full text

, , +16

The Effect of Glucocorticoids on Joint Destruction in Rheumatoid Arthritis

John Kirwan · New England Journal of Medicine · 1995 · 807 citations · Full text

, , +13

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

Zuoning Han, David L. Boyle, Lufen Chang et al. · Journal of Clinical Investigation · 2001 · 775 citations · Full text

, , +13

Role of the Mouse <i>ank</i> Gene in Control of Tissue Calcification and Arthritis

Andrew M. Ho, Michelle D. Johnson, David M. Kingsley · Science · 2000 · 647 citations

, , +14

1–5 of 1.5K

Authors

7.2K

  1. TH
    T. Huizinga

    Leiden University Medical Center, Netherlands

    29 publications · 2.7K citations

    25

    h-index

  2. GS
    Gary S. Firestein

    University of California San Diego, United States

    22 publications · 2.1K citations

    21

    h-index

  3. AH
    Annette H M van der Helm–van Mil

    Leiden University Medical Center, Netherlands

    23 publications · 2.1K citations

    21

    h-index

  4. RE
    René E. M. Toes

    Leiden University Medical Center, Netherlands

    19 publications · 1.6K citations

    19

    h-index

  5. DV
    Désirée van der Heijde

    Leiden University Medical Center, Netherlands

    19 publications · 1.4K citations

    17

    h-index

1–5 of 7.2K

Institutions

1.8K

  1. Leiden University Medical Center

    Leiden, The Netherlands

    35 h-index

    244 publications

    22.6K citations

  2. The University of Osaka

    Osaka, Japan

    25 h-index

    120 publications

    8.8K citations

  3. Inserm

    Paris, France

    25 h-index

    99 publications

    6.7K citations

  4. Lund University

    Lund, Sweden

    24 h-index

    81 publications

    5.4K citations

  5. University of California San Diego

    San Diego, United States

    24 h-index

    97 publications

    9.3K citations

  6. Radboud University Nijmegen

    Nijmegen, The Netherlands

    23 h-index

    112 publications

    17.7K citations

  7. University of Gothenburg

    Gothenburg, Sweden

    21 h-index

    142 publications

    7.3K citations

  8. Sun Yat-sen University

    Guangzhou, China

    20 h-index

    222 publications

    9.5K citations

1–8 of 1.8K

Venues

  1. Arthritis & Rheumatism

    150 publications · 16.4K citations

    74

    h-index

  2. Annals of the Rheumatic Diseases

    ARD · 97 publications · 7.3K citations

    49

    h-index

  3. PubMed

    Repository · 167 publications · 7.3K citations

    47

    h-index

  4. Arthritis Research & Therapy

    71 publications · 3.6K citations

    37

    h-index

  5. Lara D. Veeken

    45 publications · 2.8K citations

    30

    h-index

1–5