Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses

Chenguang Wang, Yukun Guan, Mengze Lv, +10

Immunity

ChromatinDouble-stranded DnaNucleic Acid ChemistryCgas-sting PathwayNatural Sciences +11

Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome

Yongyong Shi, Han Zhao, Yuhua Shi, +50

Nature Genetics

Genome-wide Association StudyGeneticsPolygenic RiskGenetic EpidemiologyPolycystic Ovary Syndrome +6

Genome-wide association analysis of thirty one production, health, reproduction and body conformation traits in contemporary U.S. Holstein cows

John B. Cole, G.R. Wiggans, Li Ma, +8

BMC Genomics

Activation of STAT6 by STING Is Critical for Antiviral Innate Immunity

Huihui Chen, Hui Sun, Fuping You, +14

Cell

InflammationAntiviral Innate ImmunityAllergyPathogenesisViral Pathogenesis +10

Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups

Yongfei Wang, Yan Zhang, Zhiming Lin, +30

Nature Communications

GeneticsImmunologyGenetic EpidemiologyHuman PolymorphismMolecular Genetics +21

Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery

Martin Philpott, Jing Yang, Tony Tumber, +9

Molecular BioSystems

Histone ModificationsEpigenetic ChangeMolecular BiologyBromodomain-peptide Displacement AssaysEpigenetics +21

Genome-wide association analysis of total cholesterol and high-density lipoprotein cholesterol levels using the Framingham Heart Study data

Li Ma, Jing Yang, Hakizumwami Birali Runesha, +4

BMC Medical Genetics

Exome sequencing identifies novel compound heterozygous mutations of IL-10 receptor 1 in neonatal-onset Crohn's disease

H Mao, Wanling Yang, Pamela Lee, +7

Genes and Immunity

InflammationChronic Inflammatory DiseasesMucosal ImmunologyNeonatal-onset CrohnImmunology +8

A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission

Tyler R. Schleicher, Jing Yang, Marianna Freudzon, +11

Nature Communications

Nonspecific DNA Binding of cGAS N Terminus Promotes cGAS Activation

Jianli Tao, Xiaowei Zhang, Jianshi Jin, +6

The Journal of Immunology