Mengze Lv

Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy

Mengze Lv, Meixia Chen, Rui Zhang et al. · Cell Research · 2020 · 1K citations · Full text

Life Sciences, Immunology, Oncology +17

Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses

Chenguang Wang, Yukun Guan, Mengze Lv et al. · Immunity · 2018 · 814 citations · Full text

Life Sciences, Microbiology, Molecular Biology +13

Manganese salts function as potent adjuvants

Rui Zhang, Chenguang Wang, Yukun Guan et al. · Cellular and Molecular Immunology · 2021 · 324 citations · Full text

Life Sciences, Immunology, Nutrition +15

Apoptotic Caspases Suppress Type I Interferon Production via the Cleavage of cGAS, MAVS, and IRF3

Xiaohan Ning, Yutao Wang, Miao Jing et al. · Molecular Cell · 2019 · 319 citations · Full text

Life Sciences, Immunology, Molecular Biology +13

Inflammasome Activation Triggers Caspase-1-Mediated Cleavage of cGAS to Regulate Responses to DNA Virus Infection

Yutao Wang, Xiaohan Ning, Pengfei Gao et al. · Immunity · 2017 · 266 citations · Full text

Life Sciences, Immunology, Microbiology +14