miR-100-5p-abundant exosomes derived from infrapatellar fat pad MSCs protect articular cartilage and ameliorate gait abnormalities via inhibition of mTOR in osteoarthritis

Jiangyi Wu, Liang Kuang, Cheng Chen, +11

Biomaterials

InflammationRegenerative MedicineMir-100-5p-abundant ExosomesMusculoskeletal ResearchAmeliorate Gait Abnormalities +10

Exosomes: roles and therapeutic potential in osteoarthritis

Zhenhong Ni, Siru Zhou, Song Li, +7

Bone Research

Therapeutic PotentialImmunologyBone RepairExtracellular MicrovesiclesOa Joint +17

The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis

Zhenhong Ni, Liang Kuang, Hangang Chen, +14

Cell Death and Disease

FGFR3/fibroblast growth factor receptor 3 inhibits autophagy through decreasing the ATG12–ATG5 conjugate, leading to the delay of cartilage development in achondroplasia

Xiaofeng Wang, Huabing Qi, Quan Wang, +12

Autophagy

Atg12–atg5 ConjugateCell GrowthOsteoporosisRegenerative MedicineCell Autophagy +15

FGFR3 deficiency enhances CXCL12-dependent chemotaxis of macrophages via upregulating CXCR7 and aggravates joint destruction in mice

Liang Kuang, Jiangyi Wu, Nan Su, +14

Annals of the Rheumatic Diseases

Long term usage of dexamethasone accelerating the initiation of osteoarthritis via enhancing the extracellular matrix calcification and apoptosis of chondrocytes

Liang Chen, Zhenhong Ni, Junlan Huang, +19

International Journal of Biological Sciences

ImmunologyOsteoporosisOrthopaedic SurgeryMusculoskeletal ResearchInflammation +19

Inhibition of aberrant Hif1α activation delays intervertebral disc degeneration in adult mice

Zuqiang Wang, Hangang Chen, Qiaoyan Tan, +19

Bone Research

Lymphatic vessels: roles and potential therapeutic intervention in rheumatoid arthritis and osteoarthritis

Siru Zhou, Guangyu Zhao, Ran Chen, +10

Theranostics

Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation

Wei Xu, Fengtao Luo, Quan Wang, +10

Journal of Bone and Mineral Research

A novel FGFR1-binding peptide exhibits anti-tumor effect on lung cancer by inhibiting proliferation and angiogenesis

Qiaoyan Tan, Zuqiang Wang, Quan Wang, +15

International Journal of Biological Sciences