miR-100-5p-abundant exosomes derived from infrapatellar fat pad MSCs protect articular cartilage and ameliorate gait abnormalities via inhibition of mTOR in osteoarthritis

Jiangyi Wu, Liang Kuang, Cheng Chen, +11

Biomaterials

InflammationRegenerative MedicineMir-100-5p-abundant ExosomesMusculoskeletal ResearchAmeliorate Gait Abnormalities +10

LncRNA HULC triggers autophagy via stabilizing Sirt1 and attenuates the chemosensitivity of HCC cells

Haojun Xiong, Zhenhong Ni, Jianzhong He, +13

Oncogene

Cell AutophagyCell RegulationImmunologyAutophagyLong Non-coding Rna +7

Exosomes: roles and therapeutic potential in osteoarthritis

Zhenhong Ni, Siru Zhou, Song Li, +7

Bone Research

Therapeutic PotentialImmunologyBone RepairExtracellular MicrovesiclesOa Joint +17

The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis

Zhenhong Ni, Liang Kuang, Hangang Chen, +14

Cell Death and Disease

The novel BH-3 mimetic apogossypolone induces Beclin-1- and ROS-mediated autophagy in human hepatocellular carcinoma cells

Ping Cheng, Zhenhong Ni, Xufang Dai, +7

Cell Death and Disease

MitophagyRos-mediated AutophagyApoptosisImmunologyCell Death +15

HCC cells with high levels of Bcl-2 are resistant to ABT-737 via activation of the ROS–JNK–autophagy pathway

Zhenhong Ni, Bin Wang, Xufang Dai, +7

Free Radical Biology and Medicine

Cell AutophagySignal TransductionSignaling PathwayCell RegulationApoptosis +10

The Bcl-2/xL inhibitor ABT-263 increases the stability of Mcl-1 mRNA and protein in hepatocellular carcinoma cells

Bin Wang, Zhenhong Ni, Xufang Dai, +5

Molecular Cancer

HSF1 upregulates ATG4B expression and enhances epirubicin-induced protective autophagy in hepatocellular carcinoma cells

Nan Zhang, Yaran Wu, Xilin Lyu, +10

Cancer Letters

Cancer ResearchCell AutophagyEpirubicin-induced Protective AutophagyMedicineLiver Physiology +10

Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway

Xianding Sun, Yang Zhou, Ruobin Zhang, +22

Nature Communications

AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells

Zhenhong Ni, Jintao He, Yaran Wu, +12

Autophagy