Control of chronic lymphocytic leukemia development by clonally-expanded CD8+ T-cells that undergo functional exhaustion in secondary lymphoid tissues

IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity

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RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

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Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells

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Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade

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Distribution and Compartmentalization of Human Circulating and Tissue-Resident Memory T Cell Subsets

Taheri Sathaliyawala, Masaru Kubota, Naomi Yudanin et al. · Immunity · 2012 · 831 citations · Full text

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