RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

L. Marty, Marc Piechaczyk, S.El Sabrouty et al. · Nucleic Acids Research · 1985 · 2.2K citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

Suzanne L. Mansour, Kirk R. Thomas, Mario R. Capecchi · Nature · 1988 · 1.7K citations

Medicine, Genetics, Molecular Genetics +15

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow.

Richard R. Hardy, Condie E. Carmack, Susan A. Shinton et al. · The Journal of Experimental Medicine · 1991 · 1.6K citations · Full text

Life Sciences, Cell Biology, Immunology +17

RAG-1 and RAG-2, Adjacent Genes That Synergistically Activate V(D)J Recombination

Marjorie A. Oettinger, David G. Schatz, Carolyn Gorka et al. · Science · 1990 · 1.5K citations

Life Sciences, Genetics, Molecular Genetics +17

The V(D)J recombination activating gene, RAG-1

David G. Schatz, Marjorie A. Oettinger, David Baltimore · Cell · 1989 · 1.2K citations · Full text

Medicine, Genetics, Molecular Genetics +11