Concepedia

Lymphocyte Development

Lymphocyte Development is a hematopoietic differentiation process in which multipotent progenitor cells give rise to mature, self-tolerant B and T lymphocytes of the adaptive immune system through ordered antigen receptor gene rearrangements, selection events, and lineage-specific maturation in primary lymphoid organs.

15K

Publications

1.2M

Citations

46.9K

Authors

4.6K

Institutions

Publications per year

2017–2026

806

Parents

Children

Publications

15K

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

Jung‐Hyun Park, Stanley Adoro, Terry I. Guinter et al. · Nature Immunology · 2010 · 5.8K citations · Full text

, , +17

Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

Laurie E. Harrington, Robin D. Hatton, Paul R. Mangan et al. · Nature Immunology · 2005 · 4.7K citations

, , +17

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

Kensuke Inaba, Muneo Inaba, Nikolaus Romani et al. · The Journal of Experimental Medicine · 1992 · 3.8K citations · Full text

, , +12

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

David L. Vaux, Suzanne Cory, Jerry M. Adams · Nature · 1988 · 3.2K citations

, , +12

RAG-1-deficient mice have no mature B and T lymphocytes

Peter Mombaerts, John Iacomini, Randall S. Johnson et al. · Cell · 1992 · 2.9K citations

, , +13

1–5 of 15K

Authors

46.9K

  1. MD
    Max D. Cooper

    University of Alabama at Birmingham, United States

    99 publications · 10.8K citations

    56

    h-index

  2. FM
    Fritz Melchers

    Institute of Molecular and Clinical Ophthalmology Basel, Switzerland

    92 publications · 10.4K citations

    55

    h-index

  3. IL
    Irving L. Weissman

    Stanford University, United States

    79 publications · 13.5K citations

    53

    h-index

  4. KR
    Klaus Rajewsky

    University of Cologne, Germany

    83 publications · 13.8K citations

    51

    h-index

  5. FW
    Frederick W. Alt

    Howard Hughes Medical Institute, United States

    74 publications · 10.3K citations

    49

    h-index

1–5 of 46.9K

Institutions

4.6K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    168 h-index

    1.6K publications

    330K citations

  2. Harvard University

    Cambridge, United States

    122 h-index

    1.7K publications

    222.2K citations

  3. National Institutes of Health

    Bethesda, United States

    119 h-index

    1.9K publications

    291.6K citations

  4. Inserm

    Paris, France

    109 h-index

    2.5K publications

    206.9K citations

  5. Stanford University

    Stanford, United States

    105 h-index

    1.1K publications

    148.3K citations

  6. Walter and Eliza Hall Institute of Medical Research

    Melbourne, Australia

    101 h-index

    1.2K publications

    161.9K citations

  7. National Cancer Institute

    Bethesda, United States

    98 h-index

    1.1K publications

    178.7K citations

  8. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    91 h-index

    1K publications

    104.9K citations

1–8 of 4.6K

Venues

  1. The Journal of Experimental Medicine

    1K publications · 147.3K citations

    198

    h-index

  2. The Journal of Immunology

    JI · 2.1K publications · 135.8K citations

    160

    h-index

  3. Blood

    1.3K publications · 106.4K citations

    154

    h-index

  4. Immunity

    280 publications · 64.5K citations

    147

    h-index

  5. Nature

    340 publications · 72K citations

    143

    h-index

1–5