Concepedia

Hematopoietic Stem Cell Commitment

Hematopoietic Stem Cell Commitment is a developmental process in which multipotent hematopoietic stem cells undergo lineage-specific differentiation decisions, thereby restricting their potential to give rise to discrete blood cell lineages, including lymphoid and myeloid cells, through the activation of specific transcriptional and epigenetic programs.

179

Publications

17K

Citations

1.3K

Authors

442

Institutions

Publications per year

2017–2026

39

Parents

Publications

179

Human haematopoietic stem cell lineage commitment is a continuous process

Lars Velten, Simon Haas, Simon Raffel et al. · Nature Cell Biology · 2017 · 928 citations · Full text

, , +12

Hematopoietic commitment during embryonic stem cell differentiation in culture.

Gordon Keller, Martin A. Kennedy, Thalia Papayannopoulou et al. · Molecular and Cellular Biology · 1993 · 901 citations · Full text

, , +17

Multilineage gene expression precedes commitment in the hemopoietic system.

Manli Hu, Diane S. Krause, M. F. Greaves et al. · Genes & Development · 1997 · 751 citations · Full text

, , +17

MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors

Brian J.P. Huntly, Hirokazu Shigematsu, Kenji Deguchi et al. · Cancer Cell · 2004 · 699 citations · Full text

, , +16

Myeloid or Lymphoid Promiscuity as a Critical Step in Hematopoietic Lineage Commitment

Toshihiro Miyamoto, Hiromi Iwasaki, Boris Reizis et al. · Developmental Cell · 2002 · 414 citations · Full text

, , +16

1–5 of 179

Authors

1.3K

  1. TE
    Tariq Enver

    University College London, United Kingdom

    6 publications · 1.1K citations

    6

    h-index

  2. IL
    Irving L. Weissman

    Stanford University, United States

    5 publications · 822 citations

    5

    h-index

  3. GK
    Gordon Keller

    University Health Network, Canada

    5 publications · 1.5K citations

    5

    h-index

  4. GS
    Guy Sauvageau

    Université de Montréal, Canada

    4 publications · 361 citations

    4

    h-index

  5. MK
    Marion Kennedy

    Icahn School of Medicine at Mount Sinai, United States

    4 publications · 569 citations

    4

    h-index

1–5 of 1.3K

Institutions

442

  1. Harvard University

    Cambridge, United States

    17 h-index

    102 publications

    12K citations

  2. Inserm

    Paris, France

    10 h-index

    63 publications

    5.4K citations

  3. Dana-Farber Cancer Institute

    Boston, United States

    10 h-index

    47 publications

    7.4K citations

  4. University of Oxford

    Oxford, United Kingdom

    9 h-index

    14 publications

    1.3K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    11 publications

    2.8K citations

  6. Université de Montréal

    Montreal, Canada

    6 h-index

    24 publications

    2.8K citations

  7. Stanford University

    Stanford, United States

    6 h-index

    22 publications

    4.6K citations

  8. University of Tsukuba

    Tsukuba, Japan

    6 h-index

    22 publications

    3.4K citations

1–8 of 442

Venues

  1. Blood

    33 publications · 3.2K citations

    28

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 10 publications · 902 citations

    10

    h-index

  3. Stem Cells

    7 publications · 253 citations

    7

    h-index

  4. Experimental Hematology

    6 publications · 392 citations

    6

    h-index

  5. The Journal of Experimental Medicine

    5 publications · 745 citations

    5

    h-index

1–5