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Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

Autoimmune DiseaseLymphocyte DevelopmentAdaptive Immune SystemImmunologyIntrathymic CytokinesAutoimmunityT Cell ImmunityCytotoxic-lineage T CellsCellular Immune ResponseMedicineCell BiologyCell SignalingRegulatory T Cell Biology