Amala Alag

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

Jung‐Hyun Park, Stanley Adoro, Terry I. Guinter et al. · Nature Immunology · 2010 · 5.8K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Foxp3 Transcription Factor Is Proapoptotic and Lethal to Developing Regulatory T Cells unless Counterbalanced by Cytokine Survival Signals

Xuguang Tai, Batu Erman, Amala Alag et al. · Immunity · 2013 · 219 citations · Full text

Life Sciences, Immunology, Molecular Biology +16

'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR

Jung‐Hyun Park, Stanley Adoro, Philip J. Lucas et al. · Nature Immunology · 2007 · 167 citations

Life Sciences, Immunology, Molecular Biology +14

Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function

Leonid A. Pobezinsky, Ruth Etzensperger, Susanna Jeurling et al. · Nature Immunology · 2015 · 151 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus

Tom M. McCaughtry, Ruth Etzensperger, Amala Alag et al. · The Journal of Experimental Medicine · 2012 · 90 citations · Full text

Life Sciences, Cell Biology, Immunology +17