Concepedia

'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR

Jung‐Hyun Park, Stanley Adoro, Philip J. Lucas, Sophia D. Sarafova, Amala Alag, Loretta L. Doan, Batu Erman, Xiaolong Liu, Wilfried Ellmeier, Rémy Bosselut,

Nature Immunology · 2007 · 167 citations · 53 references

DOI

Concepts

References

53

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

Elizabeth Tivol, Frank Borriello, Alain Schweitzer et al. · Immunity · 1995 · 2.9K citations · Full text

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Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

Kimberly S. Schluns, William C. Kieper, Stephen C. Jameson et al. · Nature Immunology · 2000 · 1.6K citations

, , +12

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

Ursula von Freeden-Jeffry, Paulo Vieira, Linda Lucian et al. · The Journal of Experimental Medicine · 1995 · 1.4K citations · Full text

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IL-7 is critical for homeostatic proliferation and survival of naïve T cells

Joyce T. Tan, Eric Dudl, Eric M. Leroy et al. · Proceedings of the National Academy of Sciences · 2001 · 955 citations · Full text

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Differential Requirements for Survival and Proliferation of CD8 Naïve or Memory T Cells

Corinne Tanchot, François A. Lemonnier, Beatrice Pérarnau et al. · Science · 1997 · 860 citations

, , +17