Sophia D. Sarafova

Deletion of CD4 and CD8 Coreceptors Permits Generation of αβT Cells that Recognize Antigens Independently of the MHC

François Van Laethem, Sophia D. Sarafova, Jung‐Hyun Park et al. · Immunity · 2007 · 174 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR

Jung‐Hyun Park, Stanley Adoro, Philip J. Lucas et al. · Nature Immunology · 2007 · 167 citations

Life Sciences, Immunology, Molecular Biology +14

Modulation of Coreceptor Transcription during Positive Selection Dictates Lineage Fate Independently of TCR/Coreceptor Specificity

Sophia D. Sarafova, Batu Erman, Qing Yu et al. · Immunity · 2005 · 64 citations · Full text

Life Sciences, Immunology, Molecular Biology +12

Negative Regulation of CD4 Gene Expression by a HES-1–c-Myb Complex

Robert D. Allen, Han K. Kim, Sophia D. Sarafova et al. · Molecular and Cellular Biology · 2001 · 60 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Coreceptor Signal Strength Regulates Positive Selection but Does Not Determine CD4/CD8 Lineage Choice in a Physiologic In Vivo Model

Batu Erman, Amala Alag, Øyvind Dahle et al. · The Journal of Immunology · 2006 · 36 citations

Life Sciences, Cell Biology, Immunology +17