Concepedia

9H-Carbazole-1-carboxamides as potent and selective JAK2 inhibitors

Kurt Zimmermann, Xiaopeng Sang, Harold Mastalerz, Walter L. Johnson, Guifen Zhang, Qingjie Liu, Douglas G. Batt, Louis J. Lombardo, Dinesh M. Vyas, George L. Trainor,

Bioorganic & Medicinal Chemistry Letters · 2015 · 11 citations · 5 references

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5

Safety and Efficacy of INCB018424, a JAK1 and JAK2 Inhibitor, in Myelofibrosis

Srđan Verstovšek, Hagop M. Kantarjian, Ruben A. Mesa et al. · New England Journal of Medicine · 2010 · 1.2K citations · Full text

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Identification of a Potent Janus Kinase 3 Inhibitor with High Selectivity within the Janus Kinase Family

Gebhard Thoma, François Nuninger, Rocco Falchetto et al. · Journal of Medicinal Chemistry · 2010 · 102 citations · Full text

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Discovery of Potent and Selective Pyrazolopyrimidine Janus Kinase 2 Inhibitors

Emily J. Hanan, Anne van Abbema, Kathy Barrett et al. · Journal of Medicinal Chemistry · 2012 · 90 citations · Full text

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Janus Kinase 2 Inhibitors. Synthesis and Characterization of a Novel Polycyclic Azaindole

Tiansheng Wang, John P. Duffy, Jian Wang et al. · Journal of Medicinal Chemistry · 2009 · 40 citations · Full text

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Replacement of pyrazol-3-yl amine hinge binder with thiazol-2-yl amine: Discovery of potent and selective JAK2 inhibitors

Stephanos Ioannidis, Michelle L. Lamb, Lynsie Almeida et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 25 citations · Full text

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