Emily J. Hanan

Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα

Emily J. Hanan, Marie-Gabrielle Braun, Robert A. Heald et al. · Journal of Medicinal Chemistry · 2022 · 119 citations · Full text

Discovery of a potent and selective Aurora kinase inhibitor

Johan D. Oslob, M.J. Romanowski, Darin A. Allen et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 107 citations · Full text

Signaling Pathway, Receptor Tyrosine Kinase, Medicine +4

Discovery and Development of Potent LFA-1/ICAM-1 Antagonist SAR 1118 as an Ophthalmic Solution for Treating Dry Eye

Min Zhong, Thomas R. Gadek, Minna Bui et al. · ACS Medicinal Chemistry Letters · 2012 · 94 citations · Full text

Ocular Disease, Immunology, Immunologic Mechanism +17

Structure of the essential inner membrane lipopolysaccharide–PbgA complex

Thomas Clairfeuille, Kerry R. Buchholz, Qingling Li et al. · Nature · 2020 · 91 citations · Full text

Proteinlipid Interaction, Engineering, Membrane Biophysics +3

Discovery of Potent and Selective Pyrazolopyrimidine Janus Kinase 2 Inhibitors

Emily J. Hanan, Anne van Abbema, Kathy Barrett et al. · Journal of Medicinal Chemistry · 2012 · 89 citations · Full text

Lead Compounds, Drug Target, Chemoprevention Strategy +19