Darin A. Allen

Development of Serine Protease Inhibitors Displaying a Multicentered Short (<2.3 Å) Hydrogen Bond Binding Mode:  Inhibitors of Urokinase-Type Plasminogen Activator and Factor Xa

Erik Verner, B.A. Katz, Jeffrey R. Spencer et al. · Journal of Medicinal Chemistry · 2001 · 124 citations · Full text

Drug Target, Bioorganic Chemistry, Serine Protease Inhibitors +19

Discovery of a potent and selective Aurora kinase inhibitor

Johan D. Oslob, M.J. Romanowski, Darin A. Allen et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 107 citations · Full text

Signaling Pathway, Receptor Tyrosine Kinase, Medicine +4

Identification of Potent and Selective Small-Molecule Inhibitors of Caspase-3 through the Use of Extended Tethering and Structure-Based Drug Design

Ingrid Choong, Willard Lew, Dennis Lee et al. · Journal of Medicinal Chemistry · 2002 · 105 citations · Full text

Drug Target, Chemical Biology, Initial Tethering Hit +17

Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets

B.A. Katz, Paul A. Sprengeler, Christine Luong et al. · Chemistry & Biology · 2001 · 67 citations · Full text

Protease Inhibitors, Protein Function, Drug Target +10

2-Aminobenzimidazoles as potent Aurora kinase inhibitors

Min Zhong, Minna Bui, Shen Wang et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 41 citations · Full text

Medicinal Chemistry, Medicine, Pharmacotherapy +5