Anne van Abbema

CS1, a Potential New Therapeutic Antibody Target for the Treatment of Multiple Myeloma

Eric D. Hsi, Roxanne Steinle, Balaji Balasa et al. · Clinical Cancer Research · 2008 · 555 citations · Full text

Anti-CS1 humanized monoclonal antibody HuLuc63 inhibits myeloma cell adhesion and induces antibody-dependent cellular cytotoxicity in the bone marrow milieu

Yu‐Tzu Tai, Myles Dillon, Weihua Song et al. · Blood · 2007 · 467 citations · Full text

A Restricted Role for TYK2 Catalytic Activity in Human Cytokine Responses Revealed by Novel TYK2-Selective Inhibitors

Sue J. Sohn, Kathy Barrett, Anne van Abbema et al. · The Journal of Immunology · 2013 · 123 citations · Full text

T-regulatory Cell, Immunology, Immune Regulation +25

Lead identification of novel and selective TYK2 inhibitors

Jun Liang, Vickie Tsui, Anne van Abbema et al. · European Journal of Medicinal Chemistry · 2013 · 122 citations · Full text

Medicinal Chemistry, Hit Identification, Biochemistry +6

Lead Optimization of a 4-Aminopyridine Benzamide Scaffold To Identify Potent, Selective, and Orally Bioavailable TYK2 Inhibitors

Jun Liang, Anne van Abbema, Mercedesz Balázs et al. · Journal of Medicinal Chemistry · 2013 · 97 citations · Full text

Pharmaceutical Research, Immunology, Lead Identification +24