Concepedia

RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6

Emmanuelle Szenker‐Ravi, Umut Altunoğlu, Marc Leushacke, Célia Bosso-Lefèvre, Muznah Khatoo, Hong Thi Tran, Thomas Naert, Rivka Noelanders, Amin Hajamohideen, Claire Bénéteau,

Nature · 2018 · 201 citations · 40 references

DOIFull text

Open access

Concepts

References

40

Crypt stem cells as the cells-of-origin of intestinal cancer

Nick Barker, Rachel A. Ridgway, Johan H. van Es et al. · Nature · 2008 · 2.2K citations

, , +14

CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo

Miguel A. Moreno-Mateos, Charles E. Vejnar, Jean-Denis Beaudoin et al. · Nature Methods · 2015 · 1.4K citations · Full text

, , +9

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

Wim de Lau, Nick Barker, Teck Yew Low et al. · Nature · 2011 · 1.3K citations

, , +9

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors

Bon‐Kyoung Koo, Maureen Spit, Ingrid Jordens et al. · Nature · 2012 · 995 citations · Full text

, , +16

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

Huai-Xiang Hao, Yang Xie, Yue Zhang et al. · Nature · 2012 · 976 citations

, , +8