Concepedia

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors

Bon‐Kyoung Koo, Maureen Spit, Ingrid Jordens, Teck Yew Low, Daniel E. Stange, Marc van de Wetering, Johan H. van Es, Shabaz Mohammed, Albert J. R. Heck, Madelon M. Maurice,

Nature · 2012 · 995 citations · 32 references

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32

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Toshiro Sato, Robert G.J. Vries, Hugo J.G. Snippert et al. · Nature · 2009 · 7.2K citations

, , +14

Identification of stem cells in small intestine and colon by marker gene Lgr5

Nick Barker, Johan H. van Es, Jeroen Kuipers et al. · Nature · 2007 · 5.7K citations

, , +16

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

Toshiro Sato, Johan H. van Es, Hugo J.G. Snippert et al. · Nature · 2010 · 2.5K citations

, , +15

Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine V. Unitarian theory of the origin of the four epithelial cell types

Hazel Cheng, C. P. Leblond · American Journal of Anatomy · 1974 · 1.7K citations

, , +13

Wnt/β-Catenin/Tcf Signaling Induces the Transcription of Axin2, a Negative Regulator of the Signaling Pathway

Eek‐hoon Jho, Tong Zhang, Claire Domon–Dell et al. · Molecular and Cellular Biology · 2002 · 1.7K citations · Full text

, , +16