Daniel E. Stange

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Toshiro Sato, Robert G.J. Vries, Hugo J.G. Snippert et al. · Nature · 2009 · 7.2K citations

Life Sciences, Cell Biology, Developmental Biology +14

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

Toshiro Sato, Daniel E. Stange, Marc Ferrante et al. · Gastroenterology · 2011 · 3.8K citations · Full text

Medicine, Cell Biology, Pathology +14

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

Toshiro Sato, Johan H. van Es, Hugo J.G. Snippert et al. · Nature · 2010 · 2.5K citations

Life Sciences, Cell Biology, Developmental Biology +15

Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro

Nick Barker, Meritxell Huch, Pekka Kujala et al. · Cell stem cell · 2010 · 1.5K citations · Full text

Life Sciences, Cell Biology, Developmental Biology +10

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

Wim de Lau, Nick Barker, Teck Yew Low et al. · Nature · 2011 · 1.3K citations

Life Sciences, Cell Biology, Molecular Biology +9