Wim de Lau

The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells

Marc van de Wetering, Elena Sancho, Cornelis L. Verweij et al. · Cell · 2002 · 2K citations · Full text

Crypt Progenitor Phenotype, Tumor Biology, Medicine +11

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

Wim de Lau, Nick Barker, Teck Yew Low et al. · Nature · 2011 · 1.3K citations

Signal Transduction, Signaling Pathway, Wnt Receptors +7

Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling

Claudia Y. Janda, Luke T. Dang, Changjiang You et al. · Nature · 2017 · 409 citations

Signal Transduction, Signaling Pathway, Medicine +5

Monoclonal Antibodies Against Lgr5 Identify Human Colorectal Cancer Stem Cells

Kristel Kemper, Pramudita R. Prasetyanti, Wim de Lau et al. · Stem Cells · 2012 · 260 citations · Full text

Peyer's Patch M Cells Derived from Lgr5⁺ Stem Cells Require SpiB and Are Induced by RankL in Cultured “Miniguts”

Wim de Lau, Pekka Kujala, Kerstin Schneeberger et al. · Molecular and Cellular Biology · 2012 · 256 citations · Full text

Lymphocyte Development, Immune Regulation, Immunology +22