Maureen Spit

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors

Bon‐Kyoung Koo, Maureen Spit, Ingrid Jordens et al. · Nature · 2012 · 967 citations · Full text

Signaling Pathway, Cell Regulation, Wnt Receptors +11

Activation of bile salt nuclear receptor FXR is repressed by pro-inflammatory cytokines activating NF-κB signaling in the intestine

Raffaella Maria Gadaleta, Bas Oldenburg, Ellen C.L. Willemsen et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2011 · 181 citations · Full text

Inflammation, Cytokine, Signal Transduction +11

The linear ubiquitin chain assembly complex regulates <scp>TRAIL</scp> ‐induced gene activation and cell death

Élodie Lafont, Chahrazade Kantari‐Mimoun, Peter Dráber et al. · The EMBO Journal · 2017 · 106 citations · Full text

<scp>RNF</scp> 43 truncations trap <scp>CK</scp> 1 to drive niche‐independent self‐renewal in cancer

Maureen Spit, Nicola Fenderico, Ingrid Jordens et al. · The EMBO Journal · 2020 · 47 citations · Full text

Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network

Zeinab Anvarian, Hisashi Nojima, Eline C van Kappel et al. · Nature Structural & Molecular Biology · 2016 · 43 citations · Full text

Signal Transduction, Wnt Signaling Network, Signaling Pathway +9