Organogenesis

Organogenesis is the embryonic developmental process in which the three primary germ layers undergo coordinated cell differentiation and morphogenesis to form the functional organs of the developing organism.

27.3K

Publications

1.9M

Citations

78.4K

Authors

Institutions

Publications per year

2017–2026

2.7K

Parents

Developmental Biology

Children

Apoptosis In DevelopmentBranching MorphogenesisCell Fate DeterminationCongenital Organ DefectsDevelopmental Signaling PathwaysEpithelial MorphogenesisEpithelial-mesenchymal InteractionsExtracellular Matrix RemodelingEye DevelopmentGerm Layer Specification

Publications

27.3K

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Toshiro Sato, Robert G.J. Vries, Hugo J.G. Snippert et al. · Nature · 2009 · 7.2K citations

Life Sciences, Cell Biology, Developmental Biology +14

Cerebral organoids model human brain development and microcephaly

Madeline A. Lancaster, Magdalena Renner, Carol-Anne Martin et al. · Nature · 2013 · 5.4K citations · Full text

Life Sciences, Developmental Biology, Neuroscience +10

The single-cell transcriptional landscape of mammalian organogenesis

Junyue Cao, Malte Spielmann, Xiaojie Qiu et al. · Nature · 2019 · 4.8K citations

Life Sciences, Cell Biology, Developmental Biology +14

Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts

Toshihisa Komori, Hideshi Yagi, Shogo Nomura et al. · Cell · 1997 · 4.2K citations · Full text

Medicine, Developmental Biology, Orthopedic Surgery +16

Novel Regulators of Bone Formation: Molecular Clones and Activities

John M. Wozney, Vicki Rosen, Anthony Celeste et al. · Science · 1988 · 3.9K citations

Medicine, Developmental Biology, Molecular Biology +13

1–5 of 27.3K

Authors

78.4K

AP
Andrew P. McMahon
Harvard University, United States
66 publications · 17.4K citations
55
h-index
GR
Gerald R. Cunha
University of California, San Francisco, United States
83 publications · 7.5K citations
53
h-index
JA
Jeffrey A. Whitsett
Cincinnati Children's Hospital Medical Center, United States
67 publications · 8.4K citations
51
h-index
DY
Didier Y. R. Stainier
University of California, San Francisco, United States
57 publications · 8.2K citations
41
h-index
BL
Brigid L.M. Hogan
Howard Hughes Medical Institute, United States
47 publications · 11.8K citations
40
h-index

1–5 of 78.4K

Institutions

1–8 of 7K

Venues

Development
1.7K publications · 224.6K citations
240
h-index
Developmental Biology
1.7K publications · 135K citations
168
h-index
Nature
269 publications · 96.2K citations
144
h-index
Proceedings of the National Academy of Sciences
PNAS · 431 publications · 60.3K citations
141
h-index
Genes & Development
150 publications · 44.1K citations
117
h-index

1–5

See also Organogenesis
Molecular Regulation	Notch Signaling Wnt Signaling Jak-stat Signaling Pathway Morphogen Gradients Mapk Signaling Mtor Signaling Mechanotransduction Pathways Transforming Growth Factor Beta Signaling In T Cell Differentiation Calcium Signaling Pi3 Kinase-akt Signaling Ephrin Reverse Signaling Bmp Signaling Inhibition Sonic Hedgehog Signaling In Axis Formation
Cellular Mechanisms	Cell Proliferation Cell Differentiation Cell Migration Apoptosis Mechanotransduction Stem Cell Niche Cell Fate Specification Asymmetric Cell Division Cellular Plasticity Cell Deformation Multicellular Self-organization Germline Crosstalk
Morphogenetic Processes	Cell Migration Epithelial-mesenchymal Interactions Apoptosis Mechanotransduction Branching Morphogenesis Neural Tube Formation Optic Cup Morphogenesis Cell Deformation
Tissue Interactions	Epithelial-mesenchymal Interactions Mechanotransduction Germline Crosstalk Spemann-mangold Organizer
Model Systems	Organoids Embryonic Stem Cells Murine Models Patient-derived Organoids Root Systems