Jean-Denis Beaudoin

CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo

Miguel A. Moreno-Mateos, Charles E. Vejnar, Jean-Denis Beaudoin et al. · Nature Methods · 2015 · 1.3K citations · Full text

Systems Biology, In Vivo Gene Therapy, Natural Sciences +8

5'-UTR G-quadruplex structures acting as translational repressors

Jean-Denis Beaudoin, Jean-Pierre Perreault · Nucleic Acids Research · 2010 · 268 citations · Full text

X-ray Crystallography, 5'-Utr G-quadruplex Structures, Genetics +18

Brd4 and P300 Confer Transcriptional Competency during Zygotic Genome Activation

Shun Hang Chan, Yin Tang, Liyun Miao et al. · Developmental Cell · 2019 · 170 citations · Full text

Exploring mRNA 3′-UTR G-quadruplexes: evidence of roles in both alternative polyadenylation and mRNA shortening

Jean-Denis Beaudoin, Jean‐Pierre Perreault · Nucleic Acids Research · 2013 · 163 citations · Full text

Analyses of mRNA structure dynamics identify embryonic gene regulatory programs

Jean-Denis Beaudoin, Eva Maria Novoa, Charles E. Vejnar et al. · Nature Structural & Molecular Biology · 2018 · 130 citations

Mrna Structure Dynamics, Functional Genomics, Developmental Biology +10