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Targeting Allostery with Avatars to Design Inhibitors Assessed by Cell Activity: Dissecting MRE11 Endo- and Exonuclease Activities

Davide Moiani, Daryl A. Ronato, Chris A. Brosey, A.S. Arvai, Aleem Syed, Jean‐Yves Masson, Elena Petricci, John A. Tainer

Methods in enzymology on CD-ROM/Methods in enzymology · 2018 · 24 citations · 86 references

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86

ATM Activation by DNA Double-Strand Breaks Through the Mre11-Rad50-Nbs1 Complex

Ji‐Hoon Lee, Tanya T. Paull · Science · 2005 · 1.4K citations

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Human CtIP promotes DNA end resection

Alessandro A. Sartori, Claudia Lukas, Julia Coates et al. · Nature · 2007 · 1.3K citations · Full text

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Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11

Katharina Schlacher, Nicole Christ, Nicolas Siaud et al. · Cell · 2011 · 1.3K citations · Full text

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Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

Jacob Falck, Julia Coates, Stephen P. Jackson · Nature · 2005 · 1.2K citations

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A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2

Katharina Schlacher, Hong Wu, Maria Jasin · Cancer Cell · 2012 · 951 citations · Full text

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