Allosteric Recognition is a molecular interaction mechanism in which the binding of a ligand at an allosteric site induces a conformational change that modulates the activity or binding affinity at a distant functional site within the same macromolecule.
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2017–2026
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An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor
Xuewu Zhang, Jodi Gureasko, Kui Shen et al. · Cell · 2006 · 1.6K citations · Full text
Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics
Tsan Sam Xiao, Junichi Takagi, Barry S. Coller et al. · Nature · 2004 · 842 citations
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Howard Hughes Medical Institute
Chevy Chase, United States
24 h-index
70 publications
14.3K citations
Yale University
New Haven, United States
22 h-index
89 publications
6.3K citations
Centre National de la Recherche Scientifique
Paris, France
19 h-index
88 publications
5.9K citations
University of California, San Francisco
San Francisco, United States
16 h-index
65 publications
9K citations
Harvard University
Cambridge, United States
16 h-index
70 publications
6.8K citations
Inserm
Paris, France
15 h-index
69 publications
4K citations
Shanghai Jiao Tong University
Shanghai, China
15 h-index
76 publications
3.5K citations
National Institutes of Health
Bethesda, United States
15 h-index
61 publications
4.6K citations
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- Journal of Biological Chemistry
JBC · 80 publications · 3.9K citations
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- Journal of Molecular Biology
JMB · 68 publications · 5.8K citations
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- Proceedings of the National Academy of Sciences
PNAS · 31 publications · 3.1K citations
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- Biochemistry
60 publications · 2.1K citations
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- Journal of the American Chemical Society
JACS · 29 publications · 2.1K citations
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