Junichi Takagi

Global Conformational Rearrangements in Integrin Extracellular Domains in Outside-In and Inside-Out Signaling

Junichi Takagi, Benjamin M. Petre, Thomas Walz et al. · Cell · 2002 · 1.2K citations · Full text

Global Conformational Rearrangements, Signal Transduction, Inside-out Signaling +14

Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics

Tsan Sam Xiao, Junichi Takagi, Barry S. Coller et al. · Nature · 2004 · 836 citations · Full text

Cell Adhesion, Molecular Biology, Cell-matrix Interaction +7

Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression

Takashi Seino, Shintaro Kawasaki, Mariko Shimokawa et al. · Cell stem cell · 2018 · 614 citations

Tumor Biology, Lineage Plasticity, Pancreatic Cancer +9

Structures of the αL I Domain and Its Complex with ICAM-1 Reveal a Shape-Shifting Pathway for Integrin Regulation

Motomu Shimaoka, Tsan Sam Xiao, Jin-huan Liu et al. · Cell · 2003 · 519 citations

Molecular Physiology, Signal Transduction, Signaling Pathway +13

Ligand-binding specificities of laminin-binding integrins: A comprehensive survey of laminin–integrin interactions using recombinant α3β1, α6β1, α7β1 and α6β4 integrins

Junichi Takagi, Maria Hayashi, Hiroyuki Ido et al. · Matrix Biology · 2006 · 377 citations

Medicinal Chemistry, Comprehensive Survey, Natural Sciences +7