Motomu Shimaoka

Structures of the αL I Domain and Its Complex with ICAM-1 Reveal a Shape-Shifting Pathway for Integrin Regulation

Motomu Shimaoka, Tsan Sam Xiao, Jin-huan Liu et al. · Cell · 2003 · 519 citations

Molecular Physiology, Signal Transduction, Signaling Pathway +13

Activation of Leukocyte β2 Integrins by Conversion from Bent to Extended Conformations

N. Nishida, Can Xie, Motomu Shimaoka et al. · Immunity · 2006 · 256 citations · Full text

Extended Conformations, Signal Transduction, Cell Adhesion +9

Identification of the target self-antigens in reperfusion injury

Ming Zhang, Elisabeth M. Alicot, Isaac M. Chiu et al. · The Journal of Experimental Medicine · 2006 · 212 citations · Full text

Tissue Destruction, Immunology, Cell Death +19

Reversibly locking a protein fold in an active conformation with a disulfide bond: Integrin αL I domains with high affinity and antagonist activity<i>in vivo</i>

Motomu Shimaoka, Chafen Lu, Roger Palframan et al. · Proceedings of the National Academy of Sciences · 2001 · 209 citations · Full text

Rolling Adhesion through an Extended Conformation of Integrin αLβ2 and Relation to α I and β I-like Domain Interaction

Azucena Salas, Motomu Shimaoka, Avi N Kogan et al. · Immunity · 2004 · 193 citations · Full text

Extended Conformation, Integrin αLβ2, I-like Domain Interaction +7