Jacob Falck

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

Jacob Falck, Julia Coates, Stephen P. Jackson · Nature · 2005 · 1.2K citations

Chromatin, Genome Instability, Conserved Modes +8

The ATM–Chk2–Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

Jacob Falck, Niels Mailand, Randi G. Syljuåsen et al. · Nature · 2001 · 1.1K citations

Genome Instability, Natural Sciences, Dna Replication +5

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

Ali Jazayeri, Jacob Falck, Claudia Lukas et al. · Nature Cell Biology · 2005 · 1K citations

Chromatin, Genome Instability, Transcriptional Regulation +13

Rapid Destruction of Human Cdc25A in Response to DNA Damage

Niels Mailand, Jacob Falck, Claudia Lukas et al. · Science · 2000 · 767 citations

Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A

Claus Storgaard Sørensen, Randi G. Syljuåsen, Jacob Falck et al. · Cancer Cell · 2003 · 550 citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +12