Human CtIP promotes DNA end resection

Alessandro A. Sartori, Claudia Lukas, Julia Coates, +6

Nature

ChromatinGenome InstabilityHuman CtipDna ReplicationMedicine +2

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

Jacob Falck, Julia Coates, Stephen P. Jackson

Nature

ChromatinGenome InstabilityConserved ModesDna DamageNatural Sciences +6

Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining

Kyle M. Miller, Jorrit Tjeertes, Julia Coates, +4

Nature Structural & Molecular Biology

ChromatinGenome InstabilityNucleic Acid ChemistryDna DamageChromatin Structure +11

Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

Yaron Galanty, Rimma Belotserkovskaya, Julia Coates, +3

Nature

ChromatinGenome InstabilityMolecular RegulationNatural SciencesGenetics +7

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells

Harveer Dev, Ting-Wei Chiang, Chloé Lescale, +26

Nature Cell Biology

ChromatinGenome InstabilityMedicineMolecular BiologyShieldin Complex Promotes +5

Replication stress induces 53BP1-containing OPT domains in G1 cells

Jeanine A. Harrigan, Rimma Belotserkovskaya, Julia Coates, +5

The Journal of Cell Biology

Molecular BiologyCell CycleIncomplete Dna ReplicationG1 CellsTranscriptional Regulation +18

RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair

Yaron Galanty, Rimma Belotserkovskaya, Julia Coates, +1

Genes & Development

Dsb-responsive Factors Mdc1ChromatinGenome InstabilityDsb SitesCell Regulation +13

PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair

Takashi Ochi, Andrew N. Blackford, Julia Coates, +9

Science

ChromatinGenome InstabilityCrystal StructureChromatin RemodelingGenetics +11

A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair

Sébastien Britton, Julia Coates, Stephen P. Jackson

The Journal of Cell Biology

EngineeringDna Double-strand BreaksMicroscopyHigh-resolution ImagingDna Analysis +15

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

Gabriel Balmus, Domenic Pilger, Julia Coates, +20

Nature Communications